Punctate inner choroidopathy (PIC) is a bilateral inflammatory disorder. It usually occurs in 20 to 30-year-old healthy myopic females.

Funduscopic findings include small, round, discrete, white-yellow spots located at the level of the retinal pigment epithelium and inner choroid, most often surrounding the disc and the macular region, and show minimal to no signs of intraocular inflammation. A serous retinal detachment may be present overlying the active lesion. The lesion heals as atrophic scars with very little pigmentation.

Macular edema and choroidal neovascular membranes may occur later in 25 % of patients.

Differential Diagnosis:

• Birdshot retinochoroidopathy and myopic degeneration
• Presumed ocular histoplasmosis syndrome
• Sarcoidosis
• Serpiginous coroiditis
• Subretinal fibrosis and uveitis syndrome
• Sympathetic uveitis
• Vogt-Koyanagi-Harada disease