Acute retinal pigment epithelitis (Krill’s Disease) is a rare, idiopathic and self-limiting benign inflammatory disorder of the retinal pigment epithelium in the macular area that affects healthy young adults.
In 75% of cases the disease is unilateral, without any signs or symptoms of intraocular inflammation. It has a good prognosis without treatment.
This disease is characterized by small lesions at the level of the retinal pigment epithelium in the macular area of one or both eyes. The pigmented spots may be surrounded by a hypo-pigmented halo that transmits fluorescence without leakage in fluorescein angiography.
The etiology of acute retinal pigment epithelitis remains unknown, but some authors suggest it may have a viral etiology, while others have suggested a correlation between ARPE and central serous chorioretinopathy.
