RETINAL AND CHOROIDAL TUMORS
Congenital Hypertrophy of the Retinal Pigment Epithelium
Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is an uncommon benign fundus lesion, which is usually asymptomatic and detected on routine ophthalmic examination.
CHRPE is the result of diffuse proliferation of pigment epithelial cells and is a well-defined lesion which is flat or slightly elevated, round, solitary, dark brown-to-black in colour, and has scalloped edges. In older patients, it may have foci of depigmentation.
No treatment is required, but if the lesion increases in diameter or gives rise to an elevated nodule, this may represent an adenoma or adenocarcinoma.
CHRPE can present in the context of familial adenomatous polyposis (Gardner's syndrome), albeit, bilaterally with multifocal, smaller, ovoid lesions.
In fluorescein angiogram lesions have blackened...