Multifocal Choroiditis

Multifocal choroiditis is an inflammatory disease that causes visual loss in 70 % of patients. It usually occurs in 30 to 60-year-old healthy myopic females. Most cases are bilateral or become bilateral over time.

Fundoscopic findings include small, round, discrete and gray-yellowish spots located at the level of the retinal pigment epithelium and choriocapillaris, most often in the mid-periphery. As these lesions age and become inactive, they become atrophic and “punched-out”.

Patients may have variable amounts of anterior segment inflammation and vitritis.

Peripapillary and macular choroidal neovascularization may occur in 25-32 % of the patients.

Differential Diagnosis

• Birdshot retinochoroidopathy and myopic degeneration
• Ocular histoplasmosis syndrome
• Sarcoidosis
• Serpiginous choroiditis
• Subretinal fibrosis and uveitis syndrome
• Sympathetic uveitis
• Vogt-Koyanagi-Harada disease