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CHORIORETINAL INFLAMMATORY DISEASES - Noninfectious Causes

Multifocal Choroiditis

Multifocal choroiditis is an inflammatory disease that causes visual loss in 70 % of patients. It usually occurs in 30 to 60-year-old healthy myopic females. Most cases are bilateral or become bilateral over time.

Fundoscopic findings include small, round, discrete and gray-yellowish spots located at the level of the retinal pigment epithelium and choriocapillaris, most often in the mid-periphery. As these lesions age and become inactive, they become atrophic and “punched-out”.

Patients may have variable amounts of anterior segment inflammation and vitritis.

Peripapillary and macular choroidal neovascularization may occur in 25-32 % of the patients.

Differential Diagnosis

  • Birdshot retinochoroidopathy and myopic degeneration
  • Ocular histoplasmosis...

Multifocal choroiditis is an inflammatory disease that causes visual loss in 70 % of patients. It usually occurs in 30 to 60-year-old healthy myopic females. Most cases are bilateral or become bilateral over time.

Fundoscopic findings include small, round, discrete and gray-yellowish spots located at the level of the retinal pigment epithelium and choriocapillaris, most often in the mid-periphery. As these lesions age and become inactive, they become atrophic and “punched-out”.

Patients may have variable amounts of anterior segment inflammation and vitritis.

Peripapillary and macular choroidal neovascularization may occur in 25-32 % of the patients.

Differential Diagnosis

  • Birdshot retinochoroidopathy and myopic degeneration
  • Ocular histoplasmosis syndrome
  • Sarcoidosis
  • Serpiginous choroiditis
  • Subretinal fibrosis and uveitis syndrome
  • Sympathetic uveitis
  • Vogt-Koyanagi-Harada disease
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Clinical Cases