Angioid streaks are usually bilateral and represent visible breaks in the Bruch’s membrane. The elastic fibers of Bruch’s membrane are charged with calcium, and this accumulation makes the layer brittle and susceptible to breaks.
Clinically they consist of dark red to brown linear bands of irregular contour, originating radially from the optic disc and extending into the periphery. Near the optic disc, a circular ring sometimes interconnects them. Retinal pigment epithelium contiguous to the borders of the streaks, can be hypopigmented or thinned. The transition regions between normal and pathological retina may have a fine stippled appearance, known as “peau d’orange”. In the mid-periphery, small depigmented subretinal deposits, known as crystalline spots, are frequently present. Other ocular...