{"id":74333,"date":"2021-11-23T16:18:12","date_gmt":"2021-11-23T16:18:12","guid":{"rendered":"https:\/\/www.atlasrleye.com\/maladie-de-stargardt\/"},"modified":"2025-07-14T23:20:48","modified_gmt":"2025-07-14T23:20:48","slug":"maladie-de-stargardt","status":"publish","type":"page","link":"https:\/\/www.atlasrleye.com\/fr\/maladie-de-stargardt\/","title":{"rendered":"MALADIE DE STARGARDT"},"content":{"rendered":"

[vc_row][vc_column][vc_custom_heading text=\u00a0\u00bbSYNDROMES ET DYSTROPHIES R\u00c9TINIENNES\u00a0\u00bb font_container=\u00a0\u00bbtag:h5|font_size:22px|text_align:center|color:%23000000″ use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb link=\u00a0\u00bburl:https%3A%2F%2Fwww.atlasrleye.com%2Ffr%2Fatlas%2F%231636632807269-1444524b-3ed4|\u00a0\u00bb][vc_text_separator title=\u00a0\u00bb\u00a0\u00bb i_icon_fontawesome=\u00a0\u00bbfas fa-eye\u00a0\u00bb i_color=\u00a0\u00bbcustom\u00a0\u00bb i_size=\u00a0\u00bblg\u00a0\u00bb color=\u00a0\u00bbcustom\u00a0\u00bb border_width=\u00a0\u00bb8″ css=\u00a0\u00bb.vc_custom_1637080776101{margin-bottom: -5px !important;}\u00a0\u00bb add_icon=\u00a0\u00bbtrue\u00a0\u00bb accent_color=\u00a0\u00bb#bababa\u00a0\u00bb i_custom_color=\u00a0\u00bb#bababa\u00a0\u00bb][vc_custom_heading source=\u00a0\u00bbpost_title\u00a0\u00bb font_container=\u00a0\u00bbtag:h1|font_size:44px|text_align:center|color:%235f1b52″ use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb]

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La maladie de Stargardt est une dystrophie maculaire juv\u00e9nile la plus commune, g\u00e9n\u00e9ralement h\u00e9r\u00e9dit\u00e9 sur le mode autosomique dominant et caract\u00e9ris\u00e9e par la perte progressive des photor\u00e9cepteurs dans la r\u00e9gion maculaire causant perte de la vision centrale.<\/p>\n

Les sympt\u00f4mes commencent dans la premi\u00e8re ou deuxi\u00e8me d\u00e9cennie de la vie, pr\u00e9sentant progression variable au cours de la maladie avec perte de la vision centrale, toutefois il y a pr\u00e9servation de la vision p\u00e9riph\u00e9rique. Les patients se plaignent de dyschromatopsie g\u00e9n\u00e9ralement accompagn\u00e9e d’un scotome central.<\/p>\n

Dans les premiers stades de la maladie, le fond est compl\u00e8tement normal. On se d\u00e9veloppe, plus tard, des alt\u00e9rations autour de la fov\u00e9a, avec un aspect granuleux de l’EPR. Ces l\u00e9sions progressent \u00e0 une atrophie de l’EPR et sont observ\u00e9es taches perimaculaires de couleur blanc-jaun\u00e2tre, sous la forme de \u00ab \u00e9cailles de poisson \u00bb, typique du fundus flavimaculatus. Ces l\u00e9sions sont g\u00e9n\u00e9ralement hiperautofluorescentes (accumulation de lipofuscine et A2E) en contraste avec r\u00e9gions atrophiques hipoautofluorescentes donnant parfois l’apparence d\u2019 \u00ab\u0153il de b\u0153uf\u00bb. L’\u00e9lectro-oculographie est normale dans les premiers stades et le GRE est g\u00e9n\u00e9ralement inf\u00e9rieure \u00e0 la normale.<\/p>\n

\u00c0 ce jour, n’existe aucun traitement efficace pour am\u00e9liorer la vision et pr\u00e9venir la progression de la maladie. Toutefois, les essais cliniques en cours avec th\u00e9rapie g\u00e9nique et cellules souches, peuvent repr\u00e9senter un grand espoir dans un avenir proche.<\/p>\n<\/div>\n

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Cas Cliniques<\/span><\/strong><\/h1>\n

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Cas Clinique 1<\/a><\/h4>\n

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Cas Clinique 2<\/a><\/h4>\n

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Cas Clinique 3<\/a><\/h4>\n

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Cas Clinique 4<\/a><\/h4>\n

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Cas Clinique 5<\/a><\/h4>\n

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Cas Clinique 6<\/a><\/h4>\n

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Cas Clinique 7<\/a><\/h4>\n

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0<\/h3><\/div> <\/div> <\/div> [\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_custom_heading text=\u00a0\u00bbSYNDROMES ET DYSTROPHIES R\u00c9TINIENNES\u00a0\u00bb font_container=\u00a0\u00bbtag:h5|font_size:22px|text_align:center|color:%23000000″ use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb link=\u00a0\u00bburl:https%3A%2F%2Fwww.atlasrleye.com%2Ffr%2Fatlas%2F%231636632807269-1444524b-3ed4|\u00a0\u00bb][vc_text_separator title=\u00a0\u00bb\u00a0\u00bb i_icon_fontawesome=\u00a0\u00bbfas fa-eye\u00a0\u00bb i_color=\u00a0\u00bbcustom\u00a0\u00bb i_size=\u00a0\u00bblg\u00a0\u00bb color=\u00a0\u00bbcustom\u00a0\u00bb border_width=\u00a0\u00bb8″ css=\u00a0\u00bb.vc_custom_1637080776101{margin-bottom: -5px !important;}\u00a0\u00bb add_icon=\u00a0\u00bbtrue\u00a0\u00bb accent_color=\u00a0\u00bb#bababa\u00a0\u00bb i_custom_color=\u00a0\u00bb#bababa\u00a0\u00bb][vc_custom_heading source=\u00a0\u00bbpost_title\u00a0\u00bb font_container=\u00a0\u00bbtag:h1|font_size:44px|text_align:center|color:%235f1b52″ use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][\/vc_column][\/vc_row][vc_row][vc_column width=\u00a0\u00bb3\/4″][vc_column_text] La maladie de Stargardt est une dystrophie maculaire juv\u00e9nile la plus commune, g\u00e9n\u00e9ralement h\u00e9r\u00e9dit\u00e9 sur […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-74333","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/pages\/74333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/comments?post=74333"}],"version-history":[{"count":8,"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/pages\/74333\/revisions"}],"predecessor-version":[{"id":118062,"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/pages\/74333\/revisions\/118062"}],"wp:attachment":[{"href":"https:\/\/www.atlasrleye.com\/fr\/wp-json\/wp\/v2\/media?parent=74333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}