{"id":74517,"date":"2021-11-23T16:05:32","date_gmt":"2021-11-23T16:05:32","guid":{"rendered":"https:\/\/www.atlasrleye.com\/con-rod-dystrophies\/"},"modified":"2025-07-14T23:08:41","modified_gmt":"2025-07-14T23:08:41","slug":"con-rod-dystrophies","status":"publish","type":"page","link":"https:\/\/www.atlasrleye.com\/en\/con-rod-dystrophies\/","title":{"rendered":"CON-ROD DYSTROPHIES"},"content":{"rendered":"

[vc_row][vc_column][vc_custom_heading text=”RETINAL DYSTROPHIES AND SYNDROMES” font_container=”tag:h5|font_size:22px|text_align:center|color:%23000000″ use_theme_fonts=”yes” link=”url:https%3A%2F%2Fwww.atlasrleye.com%2Fen%2Fatlas%2F%231636632807269-1444524b-3ed4|”][vc_text_separator title=”” i_icon_fontawesome=”fas fa-eye” i_color=”custom” i_size=”lg” color=”custom” border_width=”8″ css=”.vc_custom_1637080776101{margin-bottom: -5px !important;}” add_icon=”true” accent_color=”#bababa” i_custom_color=”#bababa”][vc_custom_heading source=”post_title” font_container=”tag:h1|font_size:44px|text_align:center|color:%235f1b52″ use_theme_fonts=”yes”]

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Cone-Rod Dystrophies (CRD) are inherited progressive diseases that cause deterioration of the cone and rod photoreceptor cells and frequently lead to blindness.<\/p>\n

The symptoms of CRD include an initial loss of color vision and visual acuity followed by nyctalopia and peripheral visual loss.<\/p>\n

There is a wide variety of phenotypical expression of this group of disorders. Fundus findings at an early stage include a normal macula or macular RPE granularity. At later stages, the fundus picture discloses a pale optic disc, peripheral bone spicule-like hyperpigmentation and generalized atrophic changes of the peripheral retina. Attenuation of the retinal vessels evolves with disease progression.<\/p>\n

Electroretinography shows the cone-isolated ERG waveform proportionally worse than the rod-isolated signal, and both are abnormal, progressing to complete extinction of detectable retinal activity using ISCEV guidelines.<\/p>\n

Examples of genes associated with cone-rod dystrophies include the ABCA4 gene associated with Stargardt disease and the ALMS1 gene associated with Alstr\u00f6m disease.<\/p>\n<\/div>\n

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Clinical Cases<\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=”.vc_custom_1752534056132{margin-bottom: 10px !important;}”]<\/p>\n

Clinical Cases<\/span><\/strong><\/h1>\n

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Clinical Case 1<\/a><\/h4>\n

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Clinical Case 2<\/a><\/h4>\n

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0<\/h3><\/div> <\/div> <\/div> [\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_custom_heading text=”RETINAL DYSTROPHIES AND SYNDROMES” font_container=”tag:h5|font_size:22px|text_align:center|color:%23000000″ use_theme_fonts=”yes” link=”url:https%3A%2F%2Fwww.atlasrleye.com%2Fen%2Fatlas%2F%231636632807269-1444524b-3ed4|”][vc_text_separator title=”” i_icon_fontawesome=”fas fa-eye” i_color=”custom” i_size=”lg” color=”custom” border_width=”8″ css=”.vc_custom_1637080776101{margin-bottom: -5px !important;}” add_icon=”true” accent_color=”#bababa” i_custom_color=”#bababa”][vc_custom_heading source=”post_title” font_container=”tag:h1|font_size:44px|text_align:center|color:%235f1b52″ use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row][vc_column width=”3\/4″][vc_column_text] Cone-Rod Dystrophies (CRD) are inherited progressive diseases that cause deterioration of the cone and rod […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-74517","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/pages\/74517","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/comments?post=74517"}],"version-history":[{"count":12,"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/pages\/74517\/revisions"}],"predecessor-version":[{"id":118057,"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/pages\/74517\/revisions\/118057"}],"wp:attachment":[{"href":"https:\/\/www.atlasrleye.com\/en\/wp-json\/wp\/v2\/media?parent=74517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}