{"id":72922,"date":"2021-11-18T15:15:13","date_gmt":"2021-11-18T15:15:13","guid":{"rendered":"https:\/\/www.atlasrleye.com\/acute-posterior-multifocal-placoid-pigment-epitheliopathy\/"},"modified":"2025-06-27T00:31:15","modified_gmt":"2025-06-27T00:31:15","slug":"acute-posterior-multifocal-placoid-pigment-epitheliopathy","status":"publish","type":"page","link":"https:\/\/www.atlasrleye.com\/en\/acute-posterior-multifocal-placoid-pigment-epitheliopathy\/","title":{"rendered":"ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY"},"content":{"rendered":"

[vc_row][vc_column][vc_custom_heading text=”CHORIORETINAL INFLAMMATORY DISEASES – NonInfectious Causes” font_container=”tag:h5|font_size:22px|text_align:center|color:%23000000″ use_theme_fonts=”yes” link=”url:https%3A%2F%2Fwww.atlasrleye.com%2Fen%2Fatlas%2F%231636632631784-8a806fcb-acbc|”][vc_text_separator title=”” i_icon_fontawesome=”fas fa-eye” i_color=”custom” i_size=”lg” color=”custom” border_width=”8″ css=”.vc_custom_1637080776101{margin-bottom: -5px !important;}” add_icon=”true” accent_color=”#bababa” i_custom_color=”#bababa”][vc_custom_heading source=”post_title” font_container=”tag:h1|font_size:44px|text_align:center|color:%235f1b52″ use_theme_fonts=”yes”]

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Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an inflammatory disorder affecting the retina, retinal pigment epithelium (RPE), and choroid It is more likely to affect healthy patients of 20-40-years of age after a systemic infection.<\/p>\n

The exact pathological origin of APMPPE remains unknown, but is believed to be a hypersensitivity-induced vasculitis and represents a primary obstruction of the choroidal circulation with secondary RPE degeneration<\/p>\n

General symptoms include metamorphopsia, photopsia, scotomas, and blurred vision.<\/p>\n

Fundus examination reveals multiple yellow-white placoid subretinal lesions of the posterior pole, usually bilateral and asymmetric. Fluorescein angiogram shows typically early-stage hypofluorescent placoid areas and late-stage hyperfluorescent lesions.<\/p>\n

It resolves in weeks to months but leaves scattered areas of RPE atrophy and hyperplasia.<\/p>\n

Differential Diagnosis:<\/p>\n