CONGENITAL AND PEDIATRIC RETINAL DISEASES
Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is an ischemic retinopathy of premature and low-birth-weight infants.
Vascularization of the retina starts by week 16 of gestation. It develops centrifugally from the optic disc towards the ora serrata. The nasal retina is usually vascularized by the 8th month of gestation, and the vascularization of the temporal ora is usually completed 1-2 months later. When a child is born prematurely with an incomplete retinal vascularization, ROP can develop.
The risk factors associated with ROP include prematurity, low birth weight and supplemental oxygen in neonatal care.
Early treatment for retinopathy of prematurity study found a prevalence of ROP in children with birth weight 1000-1250g of 44%, 751-999g of 76% and < 750g of 93%. Supplemental oxygen was also related to...