RETINAL AND CHOROIDAL TUMORS
Retinoblastoma is the most common primary intraocular malignancy in childhood, with 90% of cases diagnosed in patients younger than 5 years. A positive family history is present in 5% of children who develop this disease, so it is important to examine all newborns of parents with retinoblastoma. From a genetic standpoint three forms may be considered: familial, sporadic heritable, and non-heritable. All non-heritable retinoblastomas are unilateral, and the vast majority with familial or sporadic heritable retinoblastoma can develop bilateral disease. Early diagnosis and treatment is important for preventing metastasis.
The children may present leukocoria, strabismus, intraocular inflammation, and decreased vision. Early fundus finding is a translucent, gray to white, globular mass with dilated and tortuous retinal vessels....