Multiple Evanescent White Dot Syndrome

Multiple evanescent white dot syndrome is an acute, multifocal, usually unilateral retinopathy that is predominantly seen in 20 to30-year-old healthy females.

Patients present blurred central vision, bothersome photopsias, paracentral scotomas or enlargement of the blind spot, and headaches.

This syndrome is characterized by multiple small gray-white spots at the level of the retinal pigment epithelium in the posterior pole, sparing the fovea.

The white dots disappear spontaneously within 2 months.

Differential Diagnosis

• Acute macular neuroretinopathy
• Acute posterior multifocal placoid pigment epitheliopathy
• Acute retinal pigment epithelitis
• Acute zonal occult outer retinopathy
• Birdshot retinochoroidopathy
• Diffuse unilateral subacute neuroretinitis
• Toxoplasmosis